UK Dementia Research Institute
un-jobs.net
25 Jan 2024
Job Information
- Organisation/Company
- UK Dementia Research Institute
- Research Field
- Neurosciences
- Researcher Profile
- Recognised Researcher (R2)
- Country
- United Kingdom
- Application Deadline
- 16 Feb 2024 – 17:00 (Europe/London)
- Type of Contract
- Temporary
- Job Status
- Full-time
- Hours Per Week
- 35
- Offer Starting Date
- 1 Mar 2024
- Is the job funded through the EU Research Framework Programme?
- Not funded by an EU programme
- Reference Number
- 17720BR
- Is the Job related to staff position within a Research Infrastructure?
- No
Offer Description
Dementia is the biggest health challenge of our century.
To date there is no way to prevent it or even slow its progression, and there is an urgent need to fill the knowledge gap in our basic understanding of the diseases that cause it.
The UK Dementia Research Institute (UK DRI) is the biggest UK initiative driving forward research to fill this gap.
Rapid advances in DNA technologies and computational biology are enabling scientists to identify more and more of the subtle DNA variations that can influence a person’s risk of developing different neurodegenerative diseases. Researchers at the UK DRI at Cardiff interrogate the host of genetic variations linked with neurodegenerative diseases to make new discoveries about disease processes. They use experimental model systems along with a variety of cutting-edge experimental methods and equipment to dissect the biology of many of these genes. Building on the team’s international reputation for complex data analyses, they develop and apply advanced computational approaches that enable them to make sense of huge datasets generated by complex experiments.
We are seeking applications from highly motivated individuals for a post-doctoral Research Associate working with the groups of Prof Caleb Webber and Dr Beccano-Kelly at the Dementia Research Centre in Cardiff University. The role will be focussed on the use of iPSC models of dopaminergic neurons and other cell types to understand the molecular dysfunction and genetic influences towards Parkinson’s Disease. We are looking for an enthusiastic individual with clear goals, a proactive and flexible attitude to work, and an interest in learning new concepts and technologies. The Centre provides an excellent research environment in an international and interactive atmosphere.
You should have a PhD degree in neuroscience, stem cell research or equivalent experience. Experience in human pluripotent stem cell culture, neuronal differentiation techniques and cellular phenotyping would be highly advantageous, as would experience in cellular imaging techniques such as confocal microscopy and immunohistochemistry and/or RNA sequencing preparation.
Job Purpose
To conduct research for a Parkinson’s UK and UK Dementia Research Institute (DRI) funded project to explore cellular dysfunction regarding a novel pathway identified within neurons vulnerable in PD. The project aims to elucidate mechanisms underlying Parkinson’s disease using iPSC models and contribute to the overall research performance of the School and University, carrying out high impact research resulting in high-quality publications in international journals. To pursue excellence in research and to inspire others to do the same.
Duties and Responsibilities
Research:
To conduct research to elucidate cellular dysfunction in Parkinson’s disease using iPSC models and contribute to the overall research performance of the School and University by the production of measurable outputs including bidding for funding, publishing in national academic journals and conferences, and the recruitment and supervision of postgraduate research students.
To develop research objectives and proposals for own or joint research including research funding proposals.
To attend and or present at conferences/seminars at a local and national level as required.
To undertake administrative tasks associated with the research project, including the planning and organisation of project meetings and documentation and the implementation of procedures required to ensure accurate and timely reporting.
To prepare research ethics and research governance applications as appropriate
To review and synthesise existing research literature within the field of Parkinson’s Disease.
To participate in School research activities.
To build and create networks both internally and externally to the university, to influence decisions, explore future research requirements, and share research ideas for the benefit of research projects.
Other
To engage effectively with industrial, commercial and public sector organisations, professional institutions, other academic institutions etc., regionally and nationally to raise awareness of the School’s profile, to cultivate strategically valuable alliances, and to pursue opportunities for collaboration across a range of activities. These activities are expected to contribute to the School and the enhancement of its regional and national profile.
To undergo personal and professional development that is appropriate to and which will enhance performance.
To participate in School administration and activities to promote the School and its work to the wider University and the outside world
Any other duties not included above, but consistent with the role
Requirements
- Research Field
- Neurosciences
- Education Level
- PhD or equivalent
Skills/Qualifications
Essential Criteria
Qualifications and Education
Knowledge, Skills and Experience
– Human pluripotent stem cell culture
– Neuronal differentiation
Communication and Team Working
Other
Desirable Criteria
Additional Information
Benefits
For informal enquiries please contact Professor Caleb Webber on [email protected]
This post is full-time (35 hours per week), available from 1st January 2024 and fixed term until 31st December 2027 based at the Hadyn Ellis Building, Cathays campus.
Salary: £39,347 – £44,263 per annum (Grade 6). Appointments to roles at Cardiff University are usually made at bottom of scale unless in exceptional circumstances.
The majority of roles at Cardiff University are currently operating under “blended working” arrangements, with staff having the flexibility to work partly from home and partly from the University campus depending on specific business requirements. Discussions around these arrangements can take place after the successful candidate has been appointed.
Cardiff University offers many excellent benefits, including 45 days annual leave (incl bank holidays), local pension scheme, a cycle to work scheme and other travel initiatives, annual increments within the pay scale, and more. It is an exciting and vibrant place to work, with many different challenges and is a proud Living Wage supporter.
How we will support you in performing in this role –
There are some things that you must have before you can start this role (see ‘Essential Criteria’), but other things can be developed either through training, or just by general on-the-job experience. We want to support and develop you once you have started in the role using a combination of the following to get the best out of you:
1. Regular one-to-ones with your manager
2. An experienced and supportive team around you
3. Supporting you through job-relevant training and development that you may require
4. A mentoring scheme
Work Location(s)
- Number of offers available
- 1
- Company/Institute
- UK DRI at Cardiff University
- Country
- United Kingdom
- State/Province
- Wales
- City
- Cardiff
- Postal Code
- CF14 4XN
- Street
- Hadyn Ellis Building, Maindy Road,
- Geofield
Where to apply
- Website
- https://krb-sjobs.brassring.com/TGnewUI/Search/home/HomeWithPreLoad?PageType=Jo…
Contact
- State/Province
- Wales
- City
- Cardiff
- Website
- https://ukdri.ac.uk/
- Street
- Hadyn Ellis Building, Maindy Road,
- Postal Code
- CF14 4XN
STATUS: EXPIRED
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