University College London
Job title:
Research Fellow
Company
University College London
Job description
About us Our mission is to maximise and advocate for the holistic health of all children, young people and the adults they will become, through world-class research, education and public engagement. The UCL GOS ICH, together with its clinical partner Great Ormond Street Hospital for Children, forms the largest concentration of children’s health research outside North America. The 2024-29 GOS ICH strategy focuses on its five scientific programmes. GOS ICH’s activities include active engagement with children and families, to ensure that our work is relevant and appropriate to their needs. GOS ICH generates the funding for our research by setting out our proposals in high quality applications to public, charitable and industrial funding bodies and disseminates the results of our research by publication in the medical and scientific literature, to clinicians, policy makers and the wider public. The Institute offers world-class education and training across a wide range of teaching and life learning programmes which address the needs of students and professional groups who are interested in and undertaking work relevant to child health. GOS ICH holds an Athena SWAN Charter Gold Award.About the role An opportunity has become available to join a team of scientists researching childhood solid cancers with interests in development of new cellular therapeutics. The appointee will work within the team working predominantly on a project to develop an effective CAR-T cell immunotherapy that achieves strong target engagement and enhances CAR-T cell activation and signalling.The appointee will require a PhD and extensive prior experience of T-cell culture and working in pre-GMP development, and must possess technical skills such as molecular cloning of CAR-T cells and viral backbones, cell culture including repeat stimulation assays, and retroviral transduction in primary T cells, PCR and immune assays.Main purpose is summarised as follows:
- Lab-based research associate in a defined project to improve functionality of CAR-T technology for childhood solid cancer.
- Lead the UCL component of the Department of Defense Army Medical Research and Development Command project.
- Working within the Zayed Centre laboratories in a team of scientists with focus on development of new therapies for childhood cancer.
- Supervise associated Masters and PhD students.
The salary offered is £43,124 – £45,372 per annum. The appointment is for 6 months in the first instance but with expectation of further funding becoming available for extension. The appointee will fall under the overall line management of Professor John Anderson.About you The ideal candidate for this post will hold a PhD in biological sciences, have experience of working in a pre-GMP development, and have previous experience in T cell culture, retroviral transduction in primary T cells, PCR, and immune assays, and molecular cloning of CAR-T and viral backbones.What we offer As well as the exciting opportunities this role presents we also offer some great benefits some of which are below:41 Days holiday (including 27 days annual leave 8 bank holiday and 6 closure days)
Defined benefit career average revalued earnings pension scheme (CARE)
Cycle to work scheme and season ticket loan
On-Site nursery
On-site gym
Enhanced maternity, paternity and adoption pay
Employee assistance programme: Staff Support Service
Discounted medical insuranceOur commitment to Equality, Diversity and Inclusion As London’s Global University, we know diversity fosters creativity and innovation, and we want our community to represent the diversity of the world’s talent. We are committed to equality of opportunity, to being fair and inclusive, and to being a place where we all belong.We therefore particularly encourage applications from candidates who are likely to be underrepresented in UCL’s workforce.These include people from Black, Asian and ethnic minority backgrounds; disabled people; LGBTQI+ people; and for our Grade 9 and 10 roles, women.You can read more about our commitment to Equality, Diversity and Inclusion here : https://www.ucl.ac.uk/equality-diversity-inclusion/Available documents
Expected salary
£43124 – 45372 per year
Location
North West London
Job date
Sat, 14 Dec 2024 08:16:49 GMT
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