MRC Laboratory of Molecular Biology
Job title:
Postdoctoral Scientist – Neurobiology – Dr Anne Bertolotti – LMB 2574
Company
MRC Laboratory of Molecular Biology
Job description
Fixed term, 2 yearsThe position is for a Postdoctoral Scientist with expertise working with mouse models of degenerative diseases. You will join Dr Anne Bertolotti’s pioneering research programme, which focuses on innovative approaches to rescue cells from protein misfolding, a condition at the origin of many human diseases, including neurodegenerative diseases. One of such approaches consists in targeting eIF2a phosphatases and kinases to boost protein quality control capacity (see Tsaytler et al., 2011, Science, 332, 91-4; and Das et al., 2015, Science, 348, 239-242, Carrara, M., Sigurdardottir, A., & Bertolotti, A. (2017). Nat Struct Mol Biol, 24(9), 708-716). Krzyzosiak, A., Sigurdardottir, A. et al., A. (2018). Cell, 174(5), 1216-1228.e19; Schneider K. et al., (2020), Sep 15;32(11):108154, Cell Reports; 1.Pitera, A. P., et al,. Embo J 41, e109985 (2022); Szaruga M. et al., Nat Commun. 2023; Rai S, et al. J Cell Biol. 2024.).You will join a strong inter-disciplinary team at the LMB, which has broad expertise extending from biochemistry, structural, chemical, molecular and cell biology through to transgenic animal models of neurodegenerative diseases. The team also has an excellent record of innovative basic research leading to applications in medicine.Further information about the position may be obtained from Dr Anne Bertolotti via email:You will be ambitious, creative and fearless, able to invent new approaches to explore the unknown. You will have a PhD in neuroscience or molecular biology/genetics or pharmacology or due to complete doctoral studies within 6 months of applying. Relevant experience working with mouse models is required, and this must be best attested by at least one impactful publication. Interests in neurological diseases is desirable. It is also essential to have publications in this area.You will enjoy interacting with a dynamic interdisciplinary team sharing a passion for science and a commitment to explore the unknown.This is a two-year training and development position suitable for you if you have recently completed your doctoral studies, or you are looking to move into a new research discipline and/or need to further develop your research skills. Working with our world class scientists you will be working in an Institute renowned for its excellent scientific facilities and high-quality research.LMB has a collaborative working culture and state-of-the-art building on the Cambridge Biomedical Campus. We have on-site parking, cycle enclosures and excellent public transport links to the site. We have a staff restaurant with roof terrace and access to a Campus nursery and sports and social facilities. You will be eligible to join our defined benefit pension scheme with an employer contribution of 16%, holiday entitlement of 40.5 days per annum (including bank holidays and privilege days) and a generous employee discount scheme. We are also committed to providing training and development opportunities including support towards role-related qualifications.The LMB is a world-class research institute within UK Research and Innovation (UKRI). UKRI is nine research councils, working together across all disciplines and sectors. More information can be found at www.ukri.org and .To apply and access full details of the vacancy please click on the ‘Apply’ button above.If you are unable to apply online please contact us at .Final appointments will be subject to a pre-employment screening.We actively support equality, diversity and inclusion in all our activities, processes and culture.We are a disability inclusive employer and encourage disabled people to apply for this role. You are very welcome to contact us for information about the application process and any adjustments you may require; [email protected].£41,344 per annum
Expected salary
£41344 per year
Location
Cambridge
Job date
Sat, 08 Mar 2025 08:15:39 GMT
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